Ribostamycin sulfate
CAS No. 53797-35-6
Ribostamycin sulfate( —— )
Catalog No. M14918 CAS No. 53797-35-6
Ribostamycin is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
25MG | 43 | In Stock |
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50MG | 59 | In Stock |
|
100MG | 87 | In Stock |
|
200MG | 140 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameRibostamycin sulfate
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NoteResearch use only, not for human use.
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Brief DescriptionRibostamycin is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies.
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DescriptionRibostamycin is a broad-spectrum antimicrobial, inhibits bacterial protein synthesis at the level of 30S and 50S ribosomal subunit binding, also inhibits the chaperone activity of protein disulfide isomerase (PDI), used in pharmacokinetic and nephrotoxicity studies.(In Vitro):Ribostamycin is as an intermediate in the biosynthesis of neomycin.Ribostamycin inhibited the chaperone activity of protein disulfide isomerase (PDI), but it did not inhibit the isomerase activity.Ribostamycin is effective against both gram-positive and gram-negative cocci and bacilli including drug-resistant strains. Ribostamycin is especially effective against the gentamicin-resistant bacterium Klebsiella pneumoniae, which possesses aminoglycoside-modifying enzymes.
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In VitroRibostamycin is as an intermediate in the biosynthesis of neomycin.Ribostamycin inhibited the chaperone activity of protein disulfide isomerase (PDI), but it did not inhibit the isomerase activity.Ribostamycin is effective against both gram-positive and gram-negative cocci and bacilli including drug-resistant strains. Ribostamycin is especially effective against the gentamicin-resistant bacterium Klebsiella pneumoniae, which possesses aminoglycoside-modifying enzymes.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number53797-35-6
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Formula Weight552.55
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Molecular FormulaC17H34N4O10·H2SO4
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Purity>98% (HPLC)
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SolubilityWater: 100 mg/mL (180.97 mM)
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SMILESC1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)O)N.OS(=O)(=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Horibe T, et al. Biochem Biophys Res Commun, 2001, 289(5), 967-972.
molnova catalog
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